Hydrus Microstent combined with cataract extraction lowers IOP up to 6 months post-op

Combining cataract extraction (CE) with Hydrus Microstent (HMS) implantation can lower intraocular pressure (IOP) up to 6 months following surgery and reduce the number of glaucoma medication classes required post-operatively, according to a study presented at ASCRS 2023.

The retrospective observational cohort study found that the most common indication for HMS with CE was primary open angle glaucoma with cataract (66.2%). The mean pre-operative IOP was 23.0 ± 8.6 mmHg and post-operative IOPs at 1 day, 1 month, and 4-6 months were 15.2 ± 5.8, 13.5 ± 4.7, and 13.5 ± 3.0 mmHg, respectively. The mean IOP reduction was greatest at post-operative month 1 (10.0 mmHg, 95% CI 6.959 to 12.96, P < 0.0001), and this reduction was sustained at post-operative months 4-6 (9.6 mmHg, 95% CI 6 5.081 to 14.09, P < 0.0001). Patients were using 3.1 ± 1.0 versus 2.6 ± 1.2 medication classes pre- versus post-operatively, with a reduction of 0.5 (95% CI -0.6898 to -0.2514, P < 0.0001) medication classes.

Reference
Tanya, SM, et al. Hydrus Microstent Implantation with Combined Cataract Extraction: Medium-Term Clinical Outcomes. Presented at: ASCRS 2023.